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By rev.dennis in Linux Help BlogFirst I want to mention I installed Linux Mint 19 on a Mac running Catalina (10.15.5) using Parallels Desktop 15 for Mac Pro Edition and it would not update no matter what we did. Aptitude repositories would not install no matter what. After messing with all the suggestions from multiple forums I gave up and went to reliable Ubuntu (the god father of Linux.. lol). It is always reliable and works no matter if I install it on a laptop, virtual machine or a server. Reason I don't like Ubuntu is the bloatware.. just seems slower than other distro's but when it always works you wonder why you ever tried anything else.
When installing Ubuntu 20.04 on the Mac make sure you configure options and ensure Hypervisor is checked under the CPU section or Ubuntu install will just hang with a spinning Ubuntu circle of death but after you wait for everything to get done, it also fails with a Parallels Tools install because Parallels Desktop 15 for Mac does not support Ubuntu 20 and the newest version of Ubuntu it supports at the time of this article is 19.10 so going to try #3 which is download Ubuntu Desktop 19.10 from the archive and try to install that.
Just as a note, I am seriously considering installing the Arch Linux madjaro which looks totally awesome and I have only read great things about it but to be honest I haven't worked with pac as the software update/installer. I'm familiar with aptitude for Debian systems and yum installer for Redhat systems but pac would be all new to me so let me get Ubuntu working first then play with something new.
By rev.dennis in K8 Strong the JouneyHere we go.. last week was a rough one with Kate running a fever of 103.8 after her port placement. Then the horror of going through the Emergency Room at Harper Hutzel to then get admitted to the desired Karmanos. It was a rough week but what they did worked since Kate had a good weekend as well as Monday and Tuesday. Now we have two appointments (so far) for Wednesday and Thursday with Wednesday being the big day with Lab work, Dr consultation with Dr. Yang, chemo and then Lumbar Puncture.
By rev.dennis in Linux Help Blogffmpeg has been around for a long long long time and its still the tool many choose when wanting to convert video and/or audio especially since its free. Many of the pretty GUI applications that are out there use ffmpeg in the background but you typically will find yourself paying for the simplicity of using a GUI versus command line.
Here are some instructions on for the command line
How to reduce the file size of MPEG-4 multimedia format video with ffmpeg
Before we begin let's first get some statistics about our sample mp4 video file video1-orig.mp4
$ ffmpeg -i video1-orig.mp4 ... 17015 kb/s, 29.99 fps, 30 tbr, 90k tbn, 180k tbc (default) ...
Identify the current file, which in this case the size is 22MB:
$ ls -hl video1-orig.mp4 -rw-rw-r--. 1 user1 user1 22M Jul 23 10:56 video1-orig.mp4
The current bitrate of our mp4 video file is 17015 kb/s based on the first command you ran above (using the -i when you were looking for information about the file). The following linux command will reduce the bit rate of the above MP4 video file by approximately half and save the output as video1-new.mp4:
$ ffmpeg -i video1-orig.mp4 -b 8507k video1-new.mp4
The new size of our mp4 file is:
$ ls -hl video1-new.mp4 -rw-rw-r--. 1 user1 user1 12M Jul 23 11:14 video1-new.mp4
By rev.dennis in K8 Strong the JouneyThis week isn't about the chemo but more about a big Tuesday appointment where Kate will move
from a PICC line
to a PORT
as well as get an Bone Marrow Biopsy / MRD Test.
What is an MRD Test?
Measurable or minimal residual disease (MRD) testing is used to see if the cancer treatment is working and to guide further treatment plans. MRD testing is mainly used in blood cancers (leukemia, lymphoma and myeloma), but is being studied in other cancers. It is a type of personalized medicine, because the results can be used to tailor your treatment plan.
What can the MRD test find?
This test can find even the smallest amount of cancer cells that may be remaining after treatment. This can:
Show how well your cancer has responded to the treatment you received. Do a better job of finding out if you are in remission than other tests. Find a cancer recurrence sooner than other tests. MRD tests use highly sensitive methods, including multi-parametric flow cytometry and polymerase chain reaction (PCR). These methods look for any remaining cancer cells that cannot be seen in routine tests. This test can detect even 1 cancer cell among 1 million normal cells.
MRD testing is also useful in clinical trials for new medicines. MRD can show how well the medicine is working at treating the cancer without having to wait months to see if the cancer returns.
MRD and ALL
Part of routine testing in the treatment of pediatric and most adult ALL. Can detect relapse earlier than other tests. This allows for earlier treatment if relapse is suspected. Studies show that MRD is the best way to predict what treatments will be most helpful after the induction phase ALL treatment. MRD can also help identify patients most at risk for ALL relapse. These patients may have the best chance for a cure with a bone marrow transplant. Patients with good MRD response may be able to avoid transplant.